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Innate RIG-I signaling restores antigen presentation in tumors and overcomes T cell resistance

In recent years, therapy with immune modulating antibodies, termed immune checkpoint blockade (ICB), has revolutionized the treatment of advanced metastatic melanoma, yielding long-lasting clinical responses in a subgroup of patients. But despite this remarkable progress, resistance to therapy repre...

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Detalles Bibliográficos
Autores principales: Thier, Beatrice, Paschen, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841847/
https://www.ncbi.nlm.nih.gov/pubmed/33554047
http://dx.doi.org/10.15698/cst2021.02.242