Knockout of the circadian gene, Per2, disrupts corticosterone secretion and results in depressive‐like behaviors and deficits in startle responses

BACKGROUND: The Period Circadian Regulator 2 (Per2) gene is important for the modulation of circadian rhythms that influence biological processes. Circadian control of the hypothalamus-pituitary-adrenal (HPA) axis is critical for regulation of hormones involved in the stress response. Dysregulation...

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Detalles Bibliográficos
Autores principales: Russell, Ashley L., Miller, Lauren, Yi, Hannah, Keil, Rita, Handa, Robert J., Wu, T. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841886/
https://www.ncbi.nlm.nih.gov/pubmed/33509094
http://dx.doi.org/10.1186/s12868-020-00607-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841886/
https://www.ncbi.nlm.nih.gov/pubmed/33509094
http://dx.doi.org/10.1186/s12868-020-00607-y

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