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Successful treatment with alectinib after crizotinib-induced hepatitis in ALK-rearranged advanced lung cancer patient: a case report

BACKGROUND: Besides the clinical benefit of crizotinib in ALK-rearranged metastatic non-small cell lung cancer (NSCLC), concerns about its hepatotoxicity have arisen. It is not clear whether this is a drug class side effect or if the use of other selective ALKs inhibitors is safe after this serious...

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Detalles Bibliográficos
Autores principales: Duarte, Flávia Amaral, Rodrigues, Leonardo Brand, Paes, Flávia Rocha, Diniz, Paulo Henrique Costa, Lima, Helena Flávia Cuba de Almada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841898/
https://www.ncbi.nlm.nih.gov/pubmed/33509141
http://dx.doi.org/10.1186/s12890-020-01390-6