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Appraisal of the Antiarthritic Potential of Prazosin via Inhibition of Proinflammatory Cytokine TNF-α: A Key Player in Rheumatoid Arthritis

[Image: see text] Prazosin, a selective α(1) adrenergic receptor antagonist, with documented anti-inflammatory potential, was evaluated for its antiarthritic efficacy by targeting specifically TNF-α. The antiarthritic attribute of prazosin validated through in vitro screening comprised thermally pro...

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Detalles Bibliográficos
Autores principales: Qasim, Sumera, Alamgeer, Saleem, Muhammad, Alotaibi, Nasser Hadal, Bukhari, Syed Nasir Abbas, Alharbi, Khalid Saad, Irfan, Hafiz Muhammad, Anwar, Rukhsana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841939/
https://www.ncbi.nlm.nih.gov/pubmed/33521476
http://dx.doi.org/10.1021/acsomega.0c05698