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The miR-1185-2-3p—GOLPH3L pathway promotes glucose metabolism in breast cancer by stabilizing p53-induced SERPINE1

BACKGROUND: Phosphatidylinositol-4-phosphate-binding protein GOLPH3L is overexpressed in human ductal carcinoma of the breast, and its expression levels correlate with the prognosis of breast cancer patients. However, the roles of GOLPH3L in breast tumorigenesis remain unclear. METHODS: We assessed...

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Detalles Bibliográficos
Autores principales: Xu, Youqin, Chen, Wancheng, Liang, Jing, Zeng, Xiaoqi, Ji, Kaiyuan, Zhou, Jianlong, Liao, Shijun, Wu, Jiexian, Xing, Kongyang, He, Zilong, Yang, Yang, Liu, Qianzhen, Zhu, Pingyi, Liu, Yuchang, Li, Li, Liu, Minfeng, Chen, Wenxiao, Huang, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842049/
https://www.ncbi.nlm.nih.gov/pubmed/33509226
http://dx.doi.org/10.1186/s13046-020-01767-9