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RNF115 promotes lung adenocarcinoma through Wnt/β-catenin pathway activation by mediating APC ubiquitination

BACKGROUND: Patients with lung adenocarcinoma (LUAD) have high mortality rate and poor prognosis. The LUAD cells display increased aerobic glycolysis, which generates energy required for their survival and proliferation. Deregulation of Wnt/β-catenin signaling pathway induces the metabolism switchin...

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Detalles Bibliográficos
Autores principales: Wu, Xiao-Ting, Wang, Yu-Han, Cai, Xiao-Yue, Dong, Yun, Cui, Qing, Zhou, Ya-Ning, Yang, Xi-Wen, Lu, Wen-Feng, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842072/
https://www.ncbi.nlm.nih.gov/pubmed/33509267
http://dx.doi.org/10.1186/s40170-021-00243-y