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Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity

To dissect the mechanisms underlying the inflation of variants in the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) genome, we present a large-scale analysis of intra-host genomic diversity, which reveals that most samples exhibit heterogeneous genomic architectures, due to the interp...

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Detalles Bibliográficos
Autores principales: Graudenzi, Alex, Maspero, Davide, Angaroni, Fabrizio, Piazza, Rocco, Ramazzotti, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842190/
https://www.ncbi.nlm.nih.gov/pubmed/33532709
http://dx.doi.org/10.1016/j.isci.2021.102116