Optogenetic Tuning of Ligand Binding to The Human T cell Receptor Using The opto-ligand-TCR System

T cells are one major cell type of the immune system that use their T cell antigen receptor (TCR) to bind and respond to foreign molecules derived from pathogens. The ligand-TCR interaction half-lives determine stimulation outcome. Until recently, scientists relied on mutating either the TCR or its...

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Detalles Bibliográficos
Autores principales: Yousefi, O. Sascha, Hörner, Maximilian, Wess, Maximilian, Idstein, Vincent, Weber, Wilfried, Schamel, Wolfgang W. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2020
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842703/
https://www.ncbi.nlm.nih.gov/pubmed/33659514
http://dx.doi.org/10.21769/BioProtoc.3540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842703/
https://www.ncbi.nlm.nih.gov/pubmed/33659514
http://dx.doi.org/10.21769/BioProtoc.3540

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