Tet1 Isoforms Differentially Regulate Gene Expression, Synaptic Transmission, and Memory in the Mammalian Brain

The dynamic regulation of DNA methylation in postmitotic neurons is necessary for memory formation and other adaptive behaviors. Ten-eleven translocation 1 (TET1) plays a part in these processes by oxidizing 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), thereby initiating active DNA deme...

Descripción completa

Detalles Bibliográficos
Autores principales: Greer, C.B., Wright, J., Weiss, J.D., Lazarenko, R.M., Moran, S.P., Zhu, J., Chronister, K.S., Jin, A.Y., Kennedy, A.J., Sweatt, J.D., Kaas, G.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842754/
https://www.ncbi.nlm.nih.gov/pubmed/33262245
http://dx.doi.org/10.1523/JNEUROSCI.1821-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842754/
https://www.ncbi.nlm.nih.gov/pubmed/33262245
http://dx.doi.org/10.1523/JNEUROSCI.1821-20.2020

Ejemplares similares