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Voxelized simulation of cerebral oxygen perfusion elucidates hypoxia in aged mouse cortex

Departures of normal blood flow and metabolite distribution from the cerebral microvasculature into neuronal tissue have been implicated with age-related neurodegeneration. Mathematical models informed by spatially and temporally distributed neuroimage data are becoming instrumental for reconstructi...

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Detalles Bibliográficos
Autores principales: Hartung, Grant, Badr, Shoale, Moeini, Mohammad, Lesage, Frédéric, Kleinfeld, David, Alaraj, Ali, Linninger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842915/
https://www.ncbi.nlm.nih.gov/pubmed/33507970
http://dx.doi.org/10.1371/journal.pcbi.1008584