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Voxelized simulation of cerebral oxygen perfusion elucidates hypoxia in aged mouse cortex
Departures of normal blood flow and metabolite distribution from the cerebral microvasculature into neuronal tissue have been implicated with age-related neurodegeneration. Mathematical models informed by spatially and temporally distributed neuroimage data are becoming instrumental for reconstructi...
Autores principales: | Hartung, Grant, Badr, Shoale, Moeini, Mohammad, Lesage, Frédéric, Kleinfeld, David, Alaraj, Ali, Linninger, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842915/ https://www.ncbi.nlm.nih.gov/pubmed/33507970 http://dx.doi.org/10.1371/journal.pcbi.1008584 |
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