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ACE2 and FURIN variants are potential predictors of SARS-CoV-2 outcome: A time to implement precision medicine against COVID-19

The severity of the new COVID-19 pandemic caused by the SARS-CoV-2 virus is strikingly variable in different global populations. SARS-CoV-2 uses ACE2 as a cell receptor, TMPRSS2 protease, and FURIN peptidase to invade human cells. Here, we investigated 1,378 whole-exome sequences of individuals from...

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Detalles Bibliográficos
Autores principales: Al-Mulla, Fahd, Mohammad, Anwar, Al Madhoun, Ashraf, Haddad, Dania, Ali, Hamad, Eaaswarkhanth, Muthukrishnan, John, Sumi Elsa, Nizam, Rasheeba, Channanath, Arshad, Abu-Farha, Mohamed, Ahmad, Rasheed, Abubaker, Jehad, Thanaraj, Thangavel Alphonse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843038/
https://www.ncbi.nlm.nih.gov/pubmed/33532652
http://dx.doi.org/10.1016/j.heliyon.2021.e06133