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Mir‐488 alleviates chemoresistance and glycolysis of colorectal cancer by targeting PFKFB3

BACKGROUND: Considering the boosting effect of glycolysis on tumor chemoresistance, this investigation aimed at exploring whether miR‐488/PFKFB3 axis might reduce drug resistance of colorectal cancer (CRC) by affecting glycolysis, proliferation, migration, and invasion of CRC cells. METHOD: Totally,...

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Detalles Bibliográficos
Autores principales: Deng, Xiaojing, Li, Dapeng, Ke, Xiquan, Wang, Qizhi, Yan, Shanjun, Xue, Yongju, Wang, Qiangwu, Zheng, Hailun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843269/
https://www.ncbi.nlm.nih.gov/pubmed/32990355
http://dx.doi.org/10.1002/jcla.23578