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CKS1B promotes cell proliferation and invasion by activating STAT3/PD‐L1 and phosphorylation of Akt signaling in papillary thyroid carcinoma

OBJECTIVE: To investigate role of GKS1B and its relationship between STAT3/PD‐L1 and p‐Akt in papillary thyroid carcinoma (PTC). METHODS: Expression of GKS1B and PD‐L1 was determined in PTC cell lines. GKS1B was overexpressed or knocked down by transfection with overexpression plasmids or si‐CKS1B....

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Detalles Bibliográficos
Autores principales: Wang, Hui, Zhang, Zhengdong, Yan, Zhe, Ma, Shihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843292/
https://www.ncbi.nlm.nih.gov/pubmed/32960462
http://dx.doi.org/10.1002/jcla.23565