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Targeting evolution of antibiotic resistance by SOS response inhibition

Antibiotic resistance is acquired in response to antibiotic therapy by activating SOS-depended mutagenesis and horizontal gene transfer pathways. Compounds able to inhibit SOS response are extremely important to develop new combinatorial strategies aimed to block mutagenesis. The regulators of homol...

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Detalles Bibliográficos
Autores principales: Yakimov, Alexander, Bakhlanova, Irina, Baitin, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843400/
https://www.ncbi.nlm.nih.gov/pubmed/33552448
http://dx.doi.org/10.1016/j.csbj.2021.01.003