Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease

BACKGROUND & AIMS: Inflammatory bowel disease (IBD) is a polygenic disorder characterized principally by dysregulated inflammation impacting the gastrointestinal tract. However, there also is increasing evidence for a clinical association with stress and depression. Given the role of the hypotha...

Descripción completa

Detalles Bibliográficos
Autores principales: Lasconi, Chiara, Pahl, Matthew C., Cousminer, Diana L., Doege, Claudia A., Chesi, Alessandra, Hodge, Kenyaita M., Leonard, Michelle E., Lu, Sumei, Johnson, Matthew E., Su, Chun, Hammond, Reza K., Pippin, James A., Terry, Natalie A., Ghanem, Louis R., Leibel, Rudolph L., Wells, Andrew D., Grant, Struan F.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843407/
https://www.ncbi.nlm.nih.gov/pubmed/33069917
http://dx.doi.org/10.1016/j.jcmgh.2020.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843407/
https://www.ncbi.nlm.nih.gov/pubmed/33069917
http://dx.doi.org/10.1016/j.jcmgh.2020.10.004

Ejemplares similares