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Omeprazole improves chemosensitivity of gastric cancer cells by m(6)A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation

The curative effect for patients with advanced gastric cancer is still unsatisfactory. Proton pump inhibitors could be a promising treatment strategy that could sensitize gastric cancer cells to antitumor drugs further; however, the underlying molecular mechanism remains to be further elucidated. In...

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Detalles Bibliográficos
Autores principales: Feng, Shuitu, Qiu, Guoqin, Yang, Lihong, Feng, Lihua, Fan, Xin, Ren, Fang, Huang, Kaida, Chen, Yide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843496/
https://www.ncbi.nlm.nih.gov/pubmed/33393595
http://dx.doi.org/10.1042/BSR20200842