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Omeprazole improves chemosensitivity of gastric cancer cells by m(6)A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation
The curative effect for patients with advanced gastric cancer is still unsatisfactory. Proton pump inhibitors could be a promising treatment strategy that could sensitize gastric cancer cells to antitumor drugs further; however, the underlying molecular mechanism remains to be further elucidated. In...
Autores principales: | Feng, Shuitu, Qiu, Guoqin, Yang, Lihong, Feng, Lihua, Fan, Xin, Ren, Fang, Huang, Kaida, Chen, Yide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843496/ https://www.ncbi.nlm.nih.gov/pubmed/33393595 http://dx.doi.org/10.1042/BSR20200842 |
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