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Decrease of Clone Diversity in IgM Repertoires of HBV Chronically Infected Individuals With High Level of Viral Replication

High-throughput antibody sequencing allows in-depth insights into human antibody repertoires. To investigate the characteristics of antibody repertoires in patients with chronic HBV infection, we performed Illumina sequencing and IMGT/HighV-QUEST analysis of B lymphocytes from healthy adults and the...

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Detalles Bibliográficos
Autores principales: Hong, Binbin, Wang, Lizhi, Huang, Chunlan, Hong, Xiaoju, Liu, Alan, Li, Qiulan, Liu, Qiaoling, Su, Lili, Wang, Lixing, Wang, Chunyu, Ying, Tianlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843509/
https://www.ncbi.nlm.nih.gov/pubmed/33519772
http://dx.doi.org/10.3389/fmicb.2020.615669