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Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Non-small cell lung cancer (NSCLC) brain metastasis cell lines and in vivo models are not widely accessible. Herein we report on a direct-from patient-derived xenograft (PDX) model system of NSCLC brain metastases with genomic annotation useful for translational and mechanistic studies. Both heterot...

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Detalles Bibliográficos
Autores principales: Baschnagel, Andrew M., Kaushik, Saakshi, Durmaz, Arda, Goldstein, Steve, Ong, Irene M., Abel, Lindsey, Clark, Paul A., Gurel, Zafer, Leal, Ticiana, Buehler, Darya, Iyer, Gopal, Scott, Jacob G., Kimple, Randall J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843608/
https://www.ncbi.nlm.nih.gov/pubmed/33510214
http://dx.doi.org/10.1038/s41598-021-81832-1