Cargando…

Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Non-small cell lung cancer (NSCLC) brain metastasis cell lines and in vivo models are not widely accessible. Herein we report on a direct-from patient-derived xenograft (PDX) model system of NSCLC brain metastases with genomic annotation useful for translational and mechanistic studies. Both heterot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baschnagel, Andrew M., Kaushik, Saakshi, Durmaz, Arda, Goldstein, Steve, Ong, Irene M., Abel, Lindsey, Clark, Paul A., Gurel, Zafer, Leal, Ticiana, Buehler, Darya, Iyer, Gopal, Scott, Jacob G., Kimple, Randall J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843608/ https://www.ncbi.nlm.nih.gov/pubmed/33510214 http://dx.doi.org/10.1038/s41598-021-81832-1

Ejemplares similares

Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients
por: Abel, Lindsey, et al.
Publicado: (2021)

Patient Derived Models to Study Head and Neck Cancer Radiation Response
por: Cosper, Pippa F., et al.
Publicado: (2020)

Merkel Cell Carcinoma Analysis of Outcomes: A 30-Year Experience
por: Liang, Evan, et al.
Publicado: (2015)

Neuropsychological testing and biomarkers in the management of brain metastases
por: Baschnagel, Andrew, et al.
Publicado: (2008)

Influence of Handling Conditions on the Establishment and Propagation of Head and Neck Cancer Patient Derived Xenografts
por: Stein, Andrew P., et al.
Publicado: (2014)

MET Inhibitor Capmatinib Radiosensitizes MET Exon 14-Mutated and MET-Amplified Non-Small Cell Lung Cancer
por: Ramesh, Shrey, et al.
Publicado: (2023)

HPV impacts survival of stage IVC non-oropharyngeal HNSCC cancer patients
por: Burr, Adam R, et al.
Publicado: (2018)

Xenograft assessment of predictive biomarkers for standard head and neck cancer therapies
por: Stein, Andrew P, et al.
Publicado: (2015)

Stability of scRNA-Seq Analysis Workflows is Susceptible to Preprocessing and is Mitigated by Regularized or Supervised Approaches
por: Durmaz, Arda, et al.
Publicado: (2022)

Investigation of the effects of quercetin and xenograft on the healing of bone defects: An experimental study
por: Durmaz, Bekir, et al.
Publicado: (2023)

Acute kidney injury due to abdominal compartment syndrome caused by duodenal metastases of prostate cancer
por: Gurel, Ali
Publicado: (2015)

Integrative transcriptome analysis suggest processing of a subset of long non-coding RNAs to small RNAs
por: Jalali, Saakshi, et al.
Publicado: (2012)

Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases
por: Contreras-Zárate, María J., et al.
Publicado: (2017)

Experimental Treatment of Mucinous Peritoneal Metastases Using Patient-Derived Xenograft Models
por: Fleten, Karianne Giller, et al.
Publicado: (2020)

HPV-Associated Head and Neck Cancer: Molecular and Nano-Scale Markers for Prognosis and Therapeutic Stratification
por: Kimple, Adam J., et al.
Publicado: (2012)

Heterogeneous distribution of trastuzumab in HER2-positive xenografts and metastases: role of the tumor microenvironment
por: Baker, Jennifer Hazel Elizabeth, et al.
Publicado: (2018)

46. PAN-CANCER ANALYSIS OF ORTHOTOPIC PATIENT DERIVED XENOGRAFTS FROM BRAIN METASTASES
por: Zeng, Yu, et al.
Publicado: (2020)

Neoadjuvant therapy gains FDA approval in non-small cell lung cancer
por: Leal, Ticiana A., et al.
Publicado: (2022)

Frequent Subgraph Mining of Functional Interaction Patterns Across Multiple Cancers
por: Durmaz, Arda, et al.
Publicado: (2021)

Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy
por: Kohli, Manish, et al.
Publicado: (2015)

Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases
por: Hänel, Lorena, et al.
Publicado: (2018)

Multiple distant metastases in a case of malignant pleural mesothelioma
por: Tertemiz, Kemal Can, et al.
Publicado: (2014)

Differential efficacy of flavone acetic against liver versus lung metastases in a human tumour xenograft.
por: Pratesi, G., et al.
Publicado: (1991)

Comprehensive characterization of chemotherapeutic efficacy on metastases in the established gastric neuroendocrine cancer patient derived xenograft model
por: Jiang, Jiahua, et al.
Publicado: (2015)

4:10 Cycles of Very Low Calories Protect Against Tumor Xenografts, but Not Metastases in the Absence of Chemotherapy
por: Pomatto, Laura Corrales-Diaz, et al.
Publicado: (2020)

MmuPV1-Induced Cutaneous Squamous Cell Carcinoma Arises Preferentially from Lgr5+ Epithelial Progenitor Cells
por: Moreno, Ruben, et al.
Publicado: (2022)

Stochastic processes: from physics to finance
por: Paul, Wolfgang, et al.
Publicado: (2013)

The role of affective urgency and emotion regulation in vaping susceptibility
por: Reff, Jason, et al.
Publicado: (2021)

Identification of O-GlcNAc Modification Targets in Mouse Retinal Pericytes: Implication of p53 in Pathogenesis of Diabetic Retinopathy
por: Gurel, Zafer, et al.
Publicado: (2014)

Personalized Risk Schemes and Machine Learning to Empower Genomic Prognostication Models in Myelodysplastic Syndromes
por: Awada, Hussein, et al.
Publicado: (2022)

Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer
por: Ramani, Vishnu C., et al.
Publicado: (2019)

Some Gastrointestinal Tract Characteristics of Karayaka Ram Lambs Slaughtered at Different Weights
por: Yıldırım, Arda, et al.
Publicado: (2014)

Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer
por: Huynh, Hung, et al.
Publicado: (2015)

A simple algorithm to assess patient suitability for Calypso‐seed implantation for four‐dimensional prostate localization
por: Kimple, Randall J., et al.
Publicado: (2009)

High Glucose Alters Retinal Astrocytes Phenotype through Increased Production of Inflammatory Cytokines and Oxidative Stress
por: Shin, Eui Seok, et al.
Publicado: (2014)

Clinical Use of the Low-Molecular-Weight Heparins in Cancer Patients: Focus on the Improved Patient Outcomes
por: Chao, Bo H., et al.
Publicado: (2011)

Sticky siRNAs targeting survivin and cyclin B1 exert an antitumoral effect on melanoma subcutaneous xenografts and lung metastases
por: Kedinger, Valerie, et al.
Publicado: (2013)

A novel patient-derived organoids-based xenografts model for preclinical drug response testing in patients with colorectal liver metastases
por: Jian, Mi, et al.
Publicado: (2020)

Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival
por: Sarangi, A, et al.
Publicado: (2009)

The memory of thin polymer films generated by spin coating
por: Reiter, Günter, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dgukuvajmu1prllnq4gvu7rcst