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Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification

Neural stem/progenitor cells (NSPCs) persist over the lifespan while encountering constant challenges from age or injury related brain environmental changes like elevated oxidative stress. But how oxidative stress regulates NSPC and its neurogenic differentiation is less clear. Here we report that a...

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Detalles Bibliográficos
Autores principales: Hwang, Inah, Uchida, Hiroki, Dai, Ziwei, Li, Fei, Sanchez, Teresa, Locasale, Jason W., Cantley, Lewis C., Zheng, Hongwu, Paik, Jihye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843645/
https://www.ncbi.nlm.nih.gov/pubmed/33510167
http://dx.doi.org/10.1038/s41467-020-20839-0