TET-Mediated Epigenetic Regulation in Immune Cell Development and Disease

TET proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and further oxidation products in DNA. The oxidized methylcytosines (oxi-mCs) facilitate DNA demethylation and are also novel epigenetic marks. TET loss-of-function is strongly associated with cancer; TET2 loss-of-function...

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Detalles Bibliográficos
Autores principales: Tsiouplis, Nikolas James, Bailey, David Wesley, Chiou, Lilly Felicia, Wissink, Fiona Jane, Tsagaratou, Ageliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843795/
https://www.ncbi.nlm.nih.gov/pubmed/33520997
http://dx.doi.org/10.3389/fcell.2020.623948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843795/
https://www.ncbi.nlm.nih.gov/pubmed/33520997
http://dx.doi.org/10.3389/fcell.2020.623948

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