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Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum

In vivo interrogation of the functional role of genes implicated in colorectal cancer (CRC) is limited by the need for physiological models that mimic the disease. Here, we describe a protocol that provides the steps required for the orthotopic co-implantation of tumoral and stromal cells into the c...

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Detalles Bibliográficos
Autores principales: Kasashima, Hiroaki, Duran, Angeles, Cid-Diaz, Tania, Muta, Yu, Kinoshita, Hiroto, Batlle, Eduard, Diaz-Meco, Maria T., Moscat, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843928/
https://www.ncbi.nlm.nih.gov/pubmed/33554135
http://dx.doi.org/10.1016/j.xpro.2021.100297