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Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum
In vivo interrogation of the functional role of genes implicated in colorectal cancer (CRC) is limited by the need for physiological models that mimic the disease. Here, we describe a protocol that provides the steps required for the orthotopic co-implantation of tumoral and stromal cells into the c...
Autores principales: | Kasashima, Hiroaki, Duran, Angeles, Cid-Diaz, Tania, Muta, Yu, Kinoshita, Hiroto, Batlle, Eduard, Diaz-Meco, Maria T., Moscat, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843928/ https://www.ncbi.nlm.nih.gov/pubmed/33554135 http://dx.doi.org/10.1016/j.xpro.2021.100297 |
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