Epiregulin (EREG) and Myocardin Related Transcription Factor A (MRTF-A) Form a Feedforward Loop to Drive Hepatic Stellate Cell Activation

Trans-differentiation of quiescent hepatic stellate cells (HSC) into myofibroblast cells is considered the linchpin of liver fibrosis. A myriad of signaling pathways contribute to HSC activation and consequently liver fibrosis. Epidermal growth factor (EGF) family of cytokines signal through the cog...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyan, Dong, Wenhui, Zhang, Tianyi, Ren, Haozhen, Wang, Jinglin, Shang, Longcheng, Zhu, Zhengyi, Zhu, Wei, Shi, Xiaolei, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843934/
https://www.ncbi.nlm.nih.gov/pubmed/33520984
http://dx.doi.org/10.3389/fcell.2020.591246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843934/
https://www.ncbi.nlm.nih.gov/pubmed/33520984
http://dx.doi.org/10.3389/fcell.2020.591246

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