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MicroRNA-505, Suppressed by Oncogenic Long Non-coding RNA LINC01448, Acts as a Novel Suppressor of Glycolysis and Tumor Progression Through Inhibiting HK2 Expression in Pancreatic Cancer

Background: MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play vital regulatory roles in pancreatic cancer (PC) initiation and progression. We aimed to explore the biological functions and underlying mechanisms of miR-505-3p (miR-505) in PC. Methods: We first screened miRNA expression profil...

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Detalles Bibliográficos
Autores principales: Xu, Zhenglei, Zhang, Dingguo, Zhang, Zhuliang, Luo, Weixiang, Shi, Ruiyue, Yao, Jun, Li, Defeng, Wang, Lisheng, Liao, Bihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843961/
https://www.ncbi.nlm.nih.gov/pubmed/33520999
http://dx.doi.org/10.3389/fcell.2020.625056