High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains

Circadian variability is driven by genetics and Diversity Outbred (DO) mice is a powerful tool for examining the genetics of complex traits because their high genetic and phenotypic diversity compared to conventional mouse crosses. The DO population combines the genetic diversity of eight founder st...

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Detalles Bibliográficos
Autores principales: Kim, Sam-Moon, Vadnie, Chelsea A., Philip, Vivek M., Gagnon, Leona H., Chowdari, Kodavali V., Chesler, Elissa J., McClung, Colleen A., Logan, Ryan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843998/
https://www.ncbi.nlm.nih.gov/pubmed/33510298
http://dx.doi.org/10.1038/s41598-021-82069-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843998/
https://www.ncbi.nlm.nih.gov/pubmed/33510298
http://dx.doi.org/10.1038/s41598-021-82069-8

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