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High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains
Circadian variability is driven by genetics and Diversity Outbred (DO) mice is a powerful tool for examining the genetics of complex traits because their high genetic and phenotypic diversity compared to conventional mouse crosses. The DO population combines the genetic diversity of eight founder st...
Autores principales: | Kim, Sam-Moon, Vadnie, Chelsea A., Philip, Vivek M., Gagnon, Leona H., Chowdari, Kodavali V., Chesler, Elissa J., McClung, Colleen A., Logan, Ryan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843998/ https://www.ncbi.nlm.nih.gov/pubmed/33510298 http://dx.doi.org/10.1038/s41598-021-82069-8 |
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