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Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells

Injury and loss of oligodendrocytes can cause demyelinating diseases such as multiple sclerosis. To improve our understanding of human oligodendrocyte development, which could facilitate development of remyelination-based treatment strategies, here we describe time-course single-cell-transcriptomic...

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Detalles Bibliográficos
Autores principales: Chamling, Xitiz, Kallman, Alyssa, Fang, Weixiang, Berlinicke, Cynthia A., Mertz, Joseph L., Devkota, Prajwal, Pantoja, Itzy E. Morales, Smith, Matthew D., Ji, Zhicheng, Chang, Calvin, Kaushik, Aniruddha, Chen, Liben, Whartenby, Katharine A., Calabresi, Peter A., Mao, Hai-Quan, Ji, Hongkai, Wang, Tza-Huei, Zack, Donald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844020/
https://www.ncbi.nlm.nih.gov/pubmed/33510160
http://dx.doi.org/10.1038/s41467-021-20892-3