HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization

Associations between particular human leukocyte antigen (HLA) alleles and susceptibility to—or protection from—autoimmune diseases have been long observed. Allele-specific antigen presentation (AP) has been widely proposed as a culprit, but it is unclear whether HLA molecules might also have non-AP,...

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Detalles Bibliográficos
Autores principales: van Drongelen, Vincent, Scavuzzi, Bruna Miglioranza, Nogueira, Sarah Veloso, Miller, Frederick W., Sawalha, Amr H., Holoshitz, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844024/
https://www.ncbi.nlm.nih.gov/pubmed/33510427
http://dx.doi.org/10.1038/s41598-021-82195-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844024/
https://www.ncbi.nlm.nih.gov/pubmed/33510427
http://dx.doi.org/10.1038/s41598-021-82195-3

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