Cargando…

HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization

Associations between particular human leukocyte antigen (HLA) alleles and susceptibility to—or protection from—autoimmune diseases have been long observed. Allele-specific antigen presentation (AP) has been widely proposed as a culprit, but it is unclear whether HLA molecules might also have non-AP,...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Drongelen, Vincent, Scavuzzi, Bruna Miglioranza, Nogueira, Sarah Veloso, Miller, Frederick W., Sawalha, Amr H., Holoshitz, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844024/ https://www.ncbi.nlm.nih.gov/pubmed/33510427 http://dx.doi.org/10.1038/s41598-021-82195-3

Ejemplares similares

The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope
por: Miglioranza Scavuzzi, Bruna, et al.
Publicado: (2022)

HLA-G and the MHC Cusp Theory
por: Scavuzzi, Bruna Miglioranza, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress, Oxidative Stress, and Rheumatic Diseases
por: Miglioranza Scavuzzi, Bruna, et al.
Publicado: (2022)

Shared epitope–aryl hydrocarbon receptor crosstalk underlies the mechanism of gene–environment interaction in autoimmune arthritis
por: Fu, Jiaqi, et al.
Publicado: (2018)

Spontaneous destructive periodontitis and skeletal bone damage in transgenic mice carrying a human shared epitope-coding HLA-DRB1 allele
por: Gehlot, Prashasnika, et al.
Publicado: (2016)

Aspartic acid(70) in the HLA-DRB1 chain and shared epitope alleles partially explain the high prevalence of autoimmunity in Mexicans
por: Valdés-Corona, Luis Francisco, et al.
Publicado: (2020)

Influence of the physicochemical properties of the HLA-DRB1 shared epitope negative alleles on rheumatoid arthritis susceptibility
por: Michou, L, et al.
Publicado: (2004)

The association between juvenile autoimmune hepatitis and HLA-DRB1 alleles: Iraqi tertiary center experience
por: Ibraheem, Mohammad Fadhil, et al.
Publicado: (2021)

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles
por: Law, Soi Cheng, et al.
Publicado: (2012)

Allele specificity of structural requirement for peptides bound to HLA- DRB1*0405 and -DRB1*0406 complexes: implication for the HLA-associated susceptibility to methimazole-induced insulin autoimmune syndrome
Publicado: (1994)

HLA-DRB1 Alleles Associated with Lower Leishmaniasis Susceptibility Share Common Amino Acid Polymorphisms and Epitope Binding Repertoires
por: de Vrij, Nicky, et al.
Publicado: (2021)

A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis
por: Gourraud, Pierre-Antoine, et al.
Publicado: (2007)

The Protective Role of HLA-DRB1(∗)13 in Autoimmune Diseases
por: Bettencourt, Andreia, et al.
Publicado: (2015)

Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis
por: Michou, Laëtitia, et al.
Publicado: (2006)

PADI4 and the HLA-DRB1 shared epitope in juvenile idiopathic arthritis
por: Hisa, Kaori, et al.
Publicado: (2017)

HLA DRB101 and macrophagic myofasciitis
por: Guis, S, et al.
Publicado: (2003)

Diagnostic value of anti-cyclic citrullinated peptides and association with HLA-DRB1 shared epitope alleles in African rheumatoid arthritis patients
por: Singwe-Ngandeu, Madeleine, et al.
Publicado: (2010)

HLA-DQB1 and HLA-DRB1 Variants Confer Susceptibility to Latent Autoimmune Diabetes in Adults: Relative Predispositional Effects among Allele Groups
por: Zhang, Minting, et al.
Publicado: (2019)

HLA-DRB1 alleles in four Amerindian populations from Argentina and Paraguay
por: Parolín, Maria L., et al.
Publicado: (2009)

Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma
por: Suzuki, Misa, et al.
Publicado: (2010)

Classical HLA-DRB1 and DPB1 Alleles Account for HLA Associations with Primary Biliary Cirrhosis
por: Invernizzi, Pietro, et al.
Publicado: (2012)

Detection of the novel HLA allele, HLA‐DRB1*08:112, identified in a Danish family
por: Plesner, Annette, et al.
Publicado: (2022)

HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA- DRB1*0301 (DR3) gene
Publicado: (1996)

Allele frequency and the associations of HLA-DRB1 and HLA-DQB1 polymorphisms with pemphigus subtypes and disease severity
por: Le, Thanh Thai Van, et al.
Publicado: (2022)

Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients
por: Grunewald, Johan, et al.
Publicado: (2010)

Frequency of HLA-DRB1 alleles in rheumatoid arthritis patients in Zahedan, southeast Iran
por: Sandoughi, Mahnaz, et al.
Publicado: (2011)

Alleles of HLA-DRB1*04 Associated with Pulmonary Tuberculosis in Amazon Brazilian Population
por: Souza de Lima, Dhêmerson, et al.
Publicado: (2016)

HLA-DRB1 allele and autoantibody profiles in Japanese patients with inclusion body myositis
por: Oyama, Munenori, et al.
Publicado: (2020)

HLA-DRB1 allele impact on pediatric multiple sclerosis in a Hellenic cohort
por: Gontika, Maria, et al.
Publicado: (2020)

Interaction Analysis between HLA-DRB1 Shared Epitope Alleles and MHC Class II Transactivator CIITA Gene with Regard to Risk of Rheumatoid Arthritis
por: Ronninger, Marcus, et al.
Publicado: (2012)

Identification of HLA-DRB1*04:10 allele as risk allele for Japanese moyamoya disease and its association with autoimmune thyroid disease: A case-control study
por: Tashiro, Ryosuke, et al.
Publicado: (2019)

Association between HLA-DRB1 alleles polymorphism and hepatocellular carcinoma: a meta-analysis
por: Lin, Zhong-Hua, et al.
Publicado: (2010)

The distribution of HLA-A, -B, and -DRB1 alleles and haplotypes in inhabitants of Guizhou Province of China()
por: Pan, Qinqin, et al.
Publicado: (2011)

Protective Effect of the HLA-DRB1*13:02 Allele in Japanese Rheumatoid Arthritis Patients
por: Oka, Shomi, et al.
Publicado: (2014)

HLA-DRB1 Alleles Are Associated with the Susceptibility to Sporadic Parkinson’s Disease in Chinese Han Population
por: Sun, Congcong, et al.
Publicado: (2012)

HLA-DRB1*14 is a protective allele for multiple sclerosis in an admixed Colombian population
por: Toro, Jaime, et al.
Publicado: (2015)

Correlation Between HLA-A, B and DRB1 Alleles and Severe Fever with Thrombocytopenia Syndrome
por: Ding, Shu-jun, et al.
Publicado: (2016)

Genetic polymorphism of HLA-DRB1 alleles in Mexican mestizo patients with abdominal aortic aneurysms
por: Anaya-Ayala, Javier E., et al.
Publicado: (2019)

Characterization of the novel HLA‐DRB1*11:04:21 allele by sequencing‐based typing
por: Giustiniani, Paola, et al.
Publicado: (2022)

Characterization of the novel HLA‐DRB3*02:179N allele by sequencing‐based typing
por: Cargou, Marine, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p1i8v2jgd7tcoclecfpt11g42g