Abundancy of polymorphic CGG repeats in the human genome suggest a broad involvement in neurological disease

Expanded CGG-repeats have been linked to neurodevelopmental and neurodegenerative disorders, including the fragile X syndrome and fragile X-associated tremor/ataxia syndrome (FXTAS). We hypothesized that as of yet uncharacterised CGG-repeat expansions within the genome contribute to human disease. T...

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Detalles Bibliográficos
Autores principales: Annear, Dale J., Vandeweyer, Geert, Elinck, Ellen, Sanchis-Juan, Alba, French, Courtney E., Raymond, Lucy, Kooy, R. Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844047/
https://www.ncbi.nlm.nih.gov/pubmed/33510257
http://dx.doi.org/10.1038/s41598-021-82050-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844047/
https://www.ncbi.nlm.nih.gov/pubmed/33510257
http://dx.doi.org/10.1038/s41598-021-82050-5

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