Mononucleotide repeat expansions with non-natural polymerase substrates

Replicative strand slippage is a biological phenomenon, ubiquitous among different organisms. However, slippage events are also relevant to non-natural replication models utilizing synthetic polymerase substrates. Strand slippage may notably affect the outcome of the primer extension reaction with r...

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Detalles Bibliográficos
Autores principales: Chudinov, Alexander V., Vasiliskov, Vadim A., Kuznetsova, Viktoriya E., Lapa, Sergey A., Kolganova, Natalia A., Timofeev, Edward N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844250/
https://www.ncbi.nlm.nih.gov/pubmed/33510377
http://dx.doi.org/10.1038/s41598-021-82150-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844250/
https://www.ncbi.nlm.nih.gov/pubmed/33510377
http://dx.doi.org/10.1038/s41598-021-82150-2

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