Transcriptional coupling and repair of 8-OxoG activate a RecA-dependent checkpoint that controls the onset of sporulation in Bacillus subtilis

During sporulation Bacillus subtilis Mfd couples transcription to nucleotide excision repair (NER) to eliminate DNA distorting lesions. Here, we report a significant decline in sporulation following Mfd disruption, which was manifested in the absence of external DNA-damage suggesting that spontaneou...

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Detalles Bibliográficos
Autores principales: Suárez, Valeria P., Martínez, Lissett E., Leyva-Sánchez, Hilda C., Valenzuela-García, Luz I., Lara-Martínez, Reyna, Jiménez-García, Luis F., Ramírez-Ramírez, Norma, Obregon-Herrera, Armando, Cuéllar-Cruz, Mayra, Robleto, Eduardo A., Pedraza-Reyes, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844254/
https://www.ncbi.nlm.nih.gov/pubmed/33510358
http://dx.doi.org/10.1038/s41598-021-82247-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844254/
https://www.ncbi.nlm.nih.gov/pubmed/33510358
http://dx.doi.org/10.1038/s41598-021-82247-8

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