Investigating the causal role of MRE11A p.E506* in breast and ovarian cancer

The nuclease MRE11A is often included in genetic test panels for hereditary breast and ovarian cancer (HBOC) due to its BRCA1-related molecular function in the DNA repair pathway. However, whether MRE11A is a true predisposition gene for HBOC is still questionable. We determined to investigate this...

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Detalles Bibliográficos
Autores principales: Elkholi, Islam E., Di Iorio, Massimo, Fahiminiya, Somayyeh, Arcand, Suzanna L., Han, HyeRim, Nogué, Clara, Behl, Supriya, Hamel, Nancy, Giroux, Sylvie, de Ladurantaye, Manon, Aleynikova, Olga, Gotlieb, Walter H., Côté, Jean-François, Rousseau, François, Tonin, Patricia N., Provencher, Diane, MesMasson, Anne-Marie, Akbari, Mohammad R., Rivera, Barbara, Foulkes, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844268/
https://www.ncbi.nlm.nih.gov/pubmed/33510186
http://dx.doi.org/10.1038/s41598-021-81106-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844268/
https://www.ncbi.nlm.nih.gov/pubmed/33510186
http://dx.doi.org/10.1038/s41598-021-81106-w

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