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Multi-functionality of a tryptophan residue conserved in substrate-binding groove of GH19 chitinases

GH19 and GH22 glycoside hydrolases belonging to the lysozyme superfamily have a related structure/function. A highly conserved tryptophan residue, Trp103, located in the binding groove of a GH19 chitinase from moss Bryum coronatum (BcChi-A) appears to have a function similar to that of well-known Tr...

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Detalles Bibliográficos
Autores principales: Nagata, Takuya, Shinya, Shoko, Ohnuma, Takayuki, Fukamizo, Tamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844276/
https://www.ncbi.nlm.nih.gov/pubmed/33510258
http://dx.doi.org/10.1038/s41598-021-81903-3