Synthesis and pharmacokinetic characterisation of a fluorine-18 labelled brain shuttle peptide fusion dimeric affibody

Brain positron emission tomography (PET) imaging with radiolabelled proteins is an emerging concept that potentially enables visualization of unique molecular targets in the brain. However, the pharmacokinetics and protein radiolabelling methods remain challenging. Here, we report the performance of...

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Detalles Bibliográficos
Autores principales: Morito, Takahiro, Harada, Ryuichi, Iwata, Ren, Du, Yiqing, Okamura, Nobuyuki, Kudo, Yukitsuka, Yanai, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844286/
https://www.ncbi.nlm.nih.gov/pubmed/33510301
http://dx.doi.org/10.1038/s41598-021-82037-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844286/
https://www.ncbi.nlm.nih.gov/pubmed/33510301
http://dx.doi.org/10.1038/s41598-021-82037-2

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