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Synthesis and pharmacokinetic characterisation of a fluorine-18 labelled brain shuttle peptide fusion dimeric affibody
Brain positron emission tomography (PET) imaging with radiolabelled proteins is an emerging concept that potentially enables visualization of unique molecular targets in the brain. However, the pharmacokinetics and protein radiolabelling methods remain challenging. Here, we report the performance of...
Autores principales: | Morito, Takahiro, Harada, Ryuichi, Iwata, Ren, Du, Yiqing, Okamura, Nobuyuki, Kudo, Yukitsuka, Yanai, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844286/ https://www.ncbi.nlm.nih.gov/pubmed/33510301 http://dx.doi.org/10.1038/s41598-021-82037-2 |
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