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Calcium-Sensing Receptor Participates in High Glucose-Induced EndMT in Primary Human Aortic Endothelial Cells

OBJECTIVE: Previous studies have shown that high glucose (HG) induces endothelial cell (EC) damage via endothelial-to-mesenchymal transition (EndMT). Although the underlying mechanisms are still unclear, recent studies have demonstrated the role of calcium-sensing receptor (CaSR) in mediating EC dam...

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Detalles Bibliográficos
Autores principales: Yuan, Cheng, Ni, Lihua, Yang, Xianqin, Zhang, Changjiang, Wu, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844313/
https://www.ncbi.nlm.nih.gov/pubmed/33519531
http://dx.doi.org/10.3389/fphys.2020.629542