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Exosomes of Human Umbilical Cord MSCs Protect Against Hypoxia/Reoxygenation-Induced Pyroptosis of Cardiomyocytes via the miRNA-100-5p/FOXO3/NLRP3 Pathway

BACKGROUND: Acute myocardial infarction (AMI) is one of the leading causes of morbidity and death worldwide. Studies have indicated that microRNAs in mesenchymal stem cell (MSC)-derived exosomes are crucial for treating various diseases. METHODS: Human umbilical cord MSC (hucMSC)-derived exosomes (h...

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Detalles Bibliográficos
Autores principales: Liang, Chenyu, Liu, Yang, Xu, Huifeng, Huang, Junling, Shen, Yi, Chen, Faxiu, Luo, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844314/
https://www.ncbi.nlm.nih.gov/pubmed/33520966
http://dx.doi.org/10.3389/fbioe.2020.615850