Hierarchical Modelling of Haplotype Effects on a Phylogeny

We introduce a hierarchical model to estimate haplotype effects based on phylogenetic relationships between haplotypes and their association with observed phenotypes. In a population there are many, but not all possible, distinct haplotypes and few observations per haplotype. Further, haplotype freq...

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Detalles Bibliográficos
Autores principales: Selle, Maria Lie, Steinsland, Ingelin, Lindgren, Finn, Brajkovic, Vladimir, Cubric-Curik, Vlatka, Gorjanc, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844322/
https://www.ncbi.nlm.nih.gov/pubmed/33519886
http://dx.doi.org/10.3389/fgene.2020.531218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844322/
https://www.ncbi.nlm.nih.gov/pubmed/33519886
http://dx.doi.org/10.3389/fgene.2020.531218

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