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Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop

Ebola virus (EBOV) is responsible for numerous devastating outbreaks throughout Africa, including the 2013–2016 West African outbreak as well as the two recent outbreaks in the Democratic Republic of the Congo (DRC), one of which is ongoing. Although EBOV disease (EVD) has typically been considered...

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Detalles Bibliográficos
Autores principales: Banadyga, Logan, Zhu, Wenjun, Kailasan, Shweta, Howell, Katie A., Franaszek, Krzysztof, He, Shihua, Siragam, Vinayakumar, Cheng, Keding, Yan, Feihu, Moffat, Estella, Cao, Wenguang, Leung, Anders, Embury-Hyatt, Carissa, Aman, M. Javad, Qiu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844533/
https://www.ncbi.nlm.nih.gov/pubmed/33436428
http://dx.doi.org/10.1128/mBio.01438-20