Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Retain Activity against Multidrug-Resistant Pseudomonas aeruginosa In Vitro and In Vivo

Most antimicrobials currently in the clinical pipeline are modifications of existing classes of antibiotics and are considered short-term solutions due to the emergence of resistance. Pseudomonas aeruginosa represents a major challenge for new antimicrobial drug discovery due to its versatile lifest...

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Detalles Bibliográficos
Autores principales: Moustafa, Dina A., Wu, Ashley W., Zamora, Danniel, Daly, Seth M., Sturge, Carolyn R., Pybus, Christine, Geller, Bruce L., Goldberg, Joanna B., Greenberg, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844538/
https://www.ncbi.nlm.nih.gov/pubmed/33436433
http://dx.doi.org/10.1128/mBio.02411-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844538/
https://www.ncbi.nlm.nih.gov/pubmed/33436433
http://dx.doi.org/10.1128/mBio.02411-20

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