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Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Retain Activity against Multidrug-Resistant Pseudomonas aeruginosa In Vitro and In Vivo
Most antimicrobials currently in the clinical pipeline are modifications of existing classes of antibiotics and are considered short-term solutions due to the emergence of resistance. Pseudomonas aeruginosa represents a major challenge for new antimicrobial drug discovery due to its versatile lifest...
Autores principales: | Moustafa, Dina A., Wu, Ashley W., Zamora, Danniel, Daly, Seth M., Sturge, Carolyn R., Pybus, Christine, Geller, Bruce L., Goldberg, Joanna B., Greenberg, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844538/ https://www.ncbi.nlm.nih.gov/pubmed/33436433 http://dx.doi.org/10.1128/mBio.02411-20 |
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