Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations

Despite the effectiveness of antiretroviral (ARV) therapy, virological failure can occur in some HIV-1-infected patients in the absence of mutations in drug target genes. We previously reported that, in vitro, the lab-adapted HIV-1 NL4-3 strain can acquire resistance to the integrase inhibitor dolut...

Descripción completa

Detalles Bibliográficos
Autores principales: Hikichi, Yuta, Van Duyne, Rachel, Pham, Phuong, Groebner, Jennifer L., Wiegand, Ann, Mellors, John W., Kearney, Mary F., Freed, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844542/
https://www.ncbi.nlm.nih.gov/pubmed/33436439
http://dx.doi.org/10.1128/mBio.03134-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844542/
https://www.ncbi.nlm.nih.gov/pubmed/33436439
http://dx.doi.org/10.1128/mBio.03134-20

Ejemplares similares