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Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases

IMPORTANCE: Understanding RAS dependency and mechanisms of RAS activation in non-V600 BRAF variant cancers has important clinical implications. This is the first study to date to systematically assess RAS dependency of BRAF alterations with real-world cancer genomic databases. OBJECTIVE: To evaluate...

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Detalles Bibliográficos
Autores principales: Zhao, Yiqing, Yu, Hanzhong, Ida, Cris M., Halling, Kevin C., Kipp, Benjamin R., Geiersbach, Katherine, Rumilla, Kandelaria M., Gupta, Sounak, Lin, Ming-Tseh, Zheng, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844594/
https://www.ncbi.nlm.nih.gov/pubmed/33507258
http://dx.doi.org/10.1001/jamanetworkopen.2020.35479