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ETV6/FLT3 Fusion Is a Novel Client Protein of Hsp90

FMS-like tyrosine kinase-3 fragments from exon 14 to the end without any mutations or deletions have been reported to fuse to ETV6 (TEL) in a few cases of myeloid/lymphoid neoplasms with eosinophilia carrying a translocation t(12;13)(p13;q12). This fusion protein confers constitutive activation on t...

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Detalles Bibliográficos
Autores principales: Ly, Bui Thi Kim, Chi, Hoang Thanh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844643/
https://www.ncbi.nlm.nih.gov/pubmed/29471895
http://dx.doi.org/10.3727/096504018X15154104709325