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Upregulation and stabilization of senescence marker protein-30 by epigallocatechin gallate against tert-butyl hydroperoxide-induced liver injury in vitro and in vivo

Senescence marker protein-30 (SMP30), a novel ageing marker, suppresses oxidative stress in the liver. However, studies on phytochemical-mediated regulation of SMP30 expression are lacking. Here, we showed that epigallocatechin gallate (EGCg), a polyphenol abundant in green tea, positively regulates...

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Detalles Bibliográficos
Autores principales: Inoue, Hirofumi, Arakawa, Kohta, Tanaka, Miori, Katsumata-Tsuboi, Rie, Takahashi, Nobuyuki, Uehara, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844653/
https://www.ncbi.nlm.nih.gov/pubmed/33536712
http://dx.doi.org/10.3164/jcbn.20-119