Silencing of E3 Ubiquitin Ligase RNF8 Enhances Ionizing Radiation Sensitivity of Medulloblastoma Cells by Promoting the Deubiquitination of PCNA

DNA damage response induced by ionizing radiation (IR) is an important event involved in the sensitivity and efficiency of radiotherapy in human medulloblastoma. RNF8 is an E3 ubiquitin ligase and has key roles in the process of DNA damage and repair. Our study aimed to evaluate the effect of RNF8 i...

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Detalles Bibliográficos
Autores principales: Li, Fei, Liu, Bin, Zhou, Xiaolan, Xu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844670/
https://www.ncbi.nlm.nih.gov/pubmed/29321089
http://dx.doi.org/10.3727/096504018X15154085345907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844670/
https://www.ncbi.nlm.nih.gov/pubmed/29321089
http://dx.doi.org/10.3727/096504018X15154085345907

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